Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 11/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 11/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 11/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568924 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL569205 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL26348105 | 0.85 | THRB (0.46) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL18562452 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL10472538 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL606619 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL10453248 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL26348102 | 0.81 | THRB (0.54) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL26348120 | 0.79 | — | — | |
| SCHEMBL5858699 | 0.78 | PDK1 (0.39) | ALDH1A1TSHRPDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 721 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127414-A1 | A COSMETIC COMPOSITION FOR ACNE CONTROL AND METHODS THEREOF | L'OREAL (FR) | 2024-06-20 | — | — | WO | claimed |
| CN-113736232-A | Modified biodegradable material and preparation method thereof | 万华化学（宁波）有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-109071490-B | Piperidinyl derivatives | 默克专利股份公司 | 2021-04-06 | — | — | CN | claimed |
| EP-3448850-B1 | PIPERIDINYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | claimed |
| US-10428024-B2 | Piperidinyl derivatives | MERCK PATENT GMBH (DE) | 2019-10-01 | — | — | US | claimed |
| EP-3141284-B1 | METHOD OF STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | OREAL (FR) | 2019-08-28 | — | — | EP | claimed |
| US-20190135753-A1 | PIPERIDINYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-05-09 | — | — | US | claimed |
| WO-2017186653-A1 | PIPERIDINYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | WO | claimed |
| EP-2029237-B1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | ORÉAL L (FR) | 2016-10-12 | — | — | EP | claimed |
| US-20160074296-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE | L'OREAL (FR) | 2016-03-17 | — | — | US | claimed |
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2004-07-29 | — | — | US | claimed |
| EP-1422226-A1 | Optically active fluorine-containing compounds and processes for their production | Tosoh Corporation (JP) | 2004-05-26 | — | — | EP | claimed |
| US-20030087402-A1 | Process for the preparation of (S) - or (R) -3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid | BRIEDEN WALTER (CH) | 2003-05-08 | — | — | US | claimed |
| US-6403832-B1 | MIXING ACID WITH AMINE, PRECIPITATING SALT, AND FILTERING; GOOD OPTICAL PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-11 | — | — | US | claimed |
| WO-2002004598-A2 | IMPROVEMENT OF CELL CULTURE PERFORMANCE BY INHIBITORS OF PYRUVATE DEHYDROGENASE KINASE | IMMUNEX CORPORATION (US) | 2002-01-17 | — | — | WO | claimed |
| US-6261830-B1 | PREPARING ENANTOMER OF 3,3,3-TRIFLUORO-2-HYDROXY-2-METHYL PROPANOIC ACID FROM RACEMIC COMPOUND BY USING STEREOSELECTIVE HYDROLASE, SEPARATING COMPOUNDS, AND CONVERTING INTERMEDIATE INTO ACID | ZENECA LTD (GB) | 2001-07-17 | — | — | US | claimed |
| EP-1074539-A2 | Process for producing optically active 3,3,3,-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-07 | — | — | EP | claimed |
| EP-0904400-A2 | ENZYMATIC PROCESS FOR STEREOSELECTIVE PREPARATION OF THERAPEUTIC AMIDES | AstraZeneca AB (SE) | 1999-03-31 | — | — | EP | claimed |
| US-5684198-A | N-ARYL-2-HYDROXYPROPANAMIDES | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1997-11-04 | — | — | US | claimed |
| WO-1997038124-A2 | ENZYMATIC PROCESS FOR STEREOSELECTIVE PREPARATION OF THERAPEUTIC AMIDES | ZENECA LIMITED (GB) | 1997-10-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074296-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE | KRT18, HOGA1, CYP27B1 | ALDH1A1 175/4885TSHR 4199/4885PDK1 1029/4885 |
| US-10428024-B2 | Piperidinyl derivatives | PDK1, PDK2, PDK3 | ALDH1A1 82/4885TSHR 3331/4885PDK1 1/4885 |
| US-20190135753-A1 | PIPERIDINYL DERIVATIVES | PDK1, PDK2, PDK3 | ALDH1A1 82/4885TSHR 3331/4885PDK1 1/4885 |
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | CYP2C19, CYP2F1, CYP2B6 | ALDH1A1 898/4885TSHR 986/4885PDK1 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.