Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.57 |
| ▸ | PDE4A | P27815 | 5/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150602 | 0.82 | ADORA2B (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12413533 | 0.82 | ADORA2B (0.63) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2917584 | 0.79 | ADORA2B (0.55) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL897035 | 0.79 | ADORA2B (0.55) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7035609 | 0.74 | ADORA2B (0.52) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9432920 | 0.74 | ADORA2A (0.49) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL380135 | 0.73 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27396492 | 0.73 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18285098 | 0.73 | ADORA2A (0.55) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10506396 | 0.73 | ADORA2B (0.50) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011487-A1 | DERIVATIVES OF CYCLIC AMP AS TREATMENT FOR CANCER | UNITED STATES OF AMERICA, REPRESENTED BY THE SECRE (US) | 1989-11-30 | — | — | WO | disclosed |