Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.55 |
| ▸ | PDE4A | P27815 | 4/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917584 | 0.89 | ADORA2B (0.55) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL12413533 | 0.83 | ADORA2B (0.63) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL150602 | 0.81 | ADORA2B (0.59) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL10535015 | 0.79 | ADORA2A (0.57) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL60158 | 0.77 | ADORA2A (0.70) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7035609 | 0.75 | ADORA2B (0.52) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL59949 | 0.74 | ADORA2B (0.72) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| 1-Methylxanthine SCHEMBL27663813 | 0.74 | ADORA2B (0.77) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL941656 | 0.74 | ADORA2B (0.55) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7801074 | 0.72 | ADORA2B (0.56) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109783-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | MESOBLAST, INC. (US) | 2026-04-23 | — | — | US | disclosed |
| US-12275801-B2 | Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase | MESOBLAST, INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-20240101961-A1 | Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof | MESOBLAST, INC. (US) | 2024-03-28 | — | — | US | disclosed |
| US-20210355447-A1 | Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof | MESOBLAST, INC. (US) | 2021-11-18 | — | — | US | disclosed |
| US-20200332023-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | MESOBLAST, INC. (US) | 2020-10-22 | — | — | US | disclosed |
| US-10609922-B2 | Protection of progenitor cells and regulation of their differentiation | PROTEOBIOACTIVES PTY LTD (AU) | 2020-04-07 | — | — | US | disclosed |
| EP-2380971-B1 | PERIVASCULAR MESENCHYMAL PRECURSOR CELLS | MESOBLAST INC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-10544394-B2 | Method of increasing proliferation of bone marrow mononuclear cells expressing STRO1-dim | MESOBLAST, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-10421946-B2 | Perivascular mesenchymal precursor cells | MESOBLAST, INC. (US) | 2019-09-24 | — | — | US | disclosed |
| US-20190201444-A1 | GLYCOENGINEERING OF E-SELECTIN LIGANDS | SACKSTEIN ROBERT (US) | 2019-07-04 | — | — | US | disclosed |
| WO-2006108229-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | ANGIOBLAST SYSTEMS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060193840-A1 | Perivascular mesenchymal precursor cell induced blood vessel formation | MESOBLAST INTERNATIONAL SÀRL (CH) | 2006-08-31 | — | — | US | disclosed |
| WO-2006032075-A1 | METHOD OF ENHANCING PROLIFERATION AND/OR SURVIVAL OF MESENCHYMAL PRECURSOR CELLS (MPC) | ANGIOBLAST SYSTEMS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006032092-A1 | MULTIPOTENTIAL EXPANDED MESENCHYMAL PRECURSOR CELL PROGENY (MEMP) AND USES THEREOF | ANGIOBLAST SYSTEMS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| EP-1613741-A1 | PERIVASCULAR MESENCHYMAL PRECURSOR CELLS | Angioblast Systems Incorporated (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-1613335-A1 | PERIVASCULAR MESENCHYMAL PRECURSOR CELL INDUCED BLOOD VESSEL FORMATION | Angioblast Systems Incorporated (US) | 2006-01-11 | — | — | EP | disclosed |
| US-20050158289-A1 | Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals | ANGIOBLAST SYSTEMS, INCORPORATED | 2005-07-21 | — | — | US | disclosed |
| US-20050019911-A1 | Mesenchymal precursor cell | MEDVET SCIENCE PTY LTD (AU) | 2005-01-27 | — | — | US | disclosed |
| WO-2004084921-A1 | PERIVASCULAR MESENCHYMAL PRECURSOR CELL INDUCED BLOOD VESSEL FORMATION | ANGIOBLAST SYSTEMS INCORPORATED (US) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085630-A1 | PERIVASCULAR MESENCHYMAL PRECURSOR CELLS | ANGIOBLAST SYSTEMS INCORPORATED (US) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10609922-B2 | Protection of progenitor cells and regulation of their differentiation | CD44, MCL1, NES | ADORA2B 4107/4885ADORA2A 3677/4885PDE4A 4216/4885 |
| US-20260109783-A1 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE | ALPP, S100P, ALPG | ADORA2B 4465/4885ADORA2A 4578/4885PDE4A 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.