Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535597 | 0.82 | SIGMAR1 (0.53) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL10241118 | 0.80 | SIGMAR1 (0.57) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL28096230 | 0.76 | SIGMAR1 (0.57) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL11938943 | 0.75 | SIGMAR1 (0.65) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL9531074 | 0.74 | SIGMAR1 (0.74) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL7110331 | 0.73 | SIGMAR1 (0.53) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL10287534 | 0.73 | SIGMAR1 (0.71) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL9869529 | 0.72 | HTR1A (0.51) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL6626009 | 0.72 | SIGMAR1 (0.65) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL11932475 | 0.71 | SIGMAR1 (0.61) | SIGMAR1HTR1ADRD2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989005799-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár RT (HU) | 1989-06-29 | — | — | WO | claimed |
| WO-1989005799-A1 | NOVEL TETRAHYDROPYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár RT (HU) | 1989-06-29 | — | — | WO | disclosed |