Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865453 | 1.00 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL29392498 | 0.77 | LMNA (0.56) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL4882534 | 0.77 | LMNA (0.56) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL5313046 | 0.77 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL255601 | 0.77 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL24445380 | 0.77 | LMNA (0.56) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL29777368 | 0.77 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL9317680 | 0.77 | LMNA (0.56) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL21647917 | 0.77 | LMNA (1.00) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL4525849 | 0.77 | LMNA (0.56) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178743-A2 | Novel tritium labelled N-mustard type compounds and a process for their production | UNIVERSITY OF PITTSBURGH (US) | 1986-04-23 | — | — | EP | claimed |
| US-4795627-A | AZIRIDINIUM ANALOG USED TO EVALUATE THE MECHANISM OF NEUROTRANSMITTER REGULATION | UNIVERSITY OF PITTSBURGH (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0178743-A2 | Novel tritium labelled N-mustard type compounds and a process for their production | UNIVERSITY OF PITTSBURGH (US) | 1986-04-23 | — | — | EP | disclosed |