Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329628 | 0.79 | LMNA (0.65) | LMNAMAPK1CES2CES1TSHR | |
| SCHEMBL18869856 | 0.79 | LMNA (0.65) | LMNAMAPK1CES2CES1TSHR | |
| SCHEMBL20271379 | 0.79 | LMNA (0.52) | LMNAMAPK1CES2CES1TSHR | |
| SCHEMBL10625669 | 0.79 | LMNA (0.52) | LMNAMAPK1CES2CES1TSHR | |
| SCHEMBL4073357 | 0.79 | LMNA (0.65) | LMNAMAPK1CES2CES1TSHR | |
| Hydrochloric Acid SCHEMBL9617550 | 0.77 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL28835827 | 0.77 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL10865453 | 0.77 | LMNA (0.62) | LMNAMAPK1CES2CES1TSHR | |
| SCHEMBL10536611 | 0.77 | LMNA (0.62) | LMNAMAPK1CES2CES1TSHR | |
| Oxalic Acid SCHEMBL28129989 | 0.75 | LMNA (0.60) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376684-A | Aminobutyric acid antagonist; antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |