Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049713 | 0.95 | LMNA (0.52) | HSD17B10LMNAMAPTNPC1RAB9A | |
| SCHEMBL7776949 | 0.86 | NPC1 (0.50) | HSD17B10LMNAMAPTNPC1RAB9A | |
| SCHEMBL19724336 | 0.85 | THRB (0.50) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL7531617 | 0.84 | NPC1 (0.48) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL10541266 | 0.83 | L3MBTL1 (0.56) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL29325164 | 0.83 | NPC1 (0.47) | HSD17B10LMNAMAPTNPC1RAB9A | |
| SCHEMBL29168891 | 0.82 | CA12 (0.51) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL9065504 | 0.82 | CA12 (0.57) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL472165 | 0.82 | CA12 (0.57) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL6942993 | 0.81 | ADRB2 (0.43) | MAPTNPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4834907-A | STABLE, HIGH RESPONSE RATE | CHISSO CORPORATION (JP) | 1989-05-30 | — | — | US | disclosed |