Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012856 | 0.82 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL10687652 | 0.81 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL536216 | 0.79 | — | — | |
| SCHEMBL6476278 | 0.79 | TDP1 (0.48) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL4676714 | 0.79 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL10012268 | 0.79 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL4676717 | 0.79 | TSHR (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL3441171 | 0.79 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL24242074 | 0.78 | TDP1 (0.37) | TDP1TSHRCYP3A4 | |
| SCHEMBL10380589 | 0.78 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814492-A | Method of preparing alkyl acrylates | TEXACO INC. (US) | 1989-03-21 | — | — | US | claimed |
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| US-20090012100-A1 | Selective Insecticides Based on Substituted Cyclic Ketoenols and Safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-01-08 | — | — | US | disclosed |
| US-20090012100-A1 | Selective Insecticides Based on Substituted Cyclic Ketoenols and Safeners | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-01-08 | — | — | US | disclosed |
| US-4814492-A | Method of preparing alkyl acrylates | TEXACO INC. (US) | 1989-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012100-A1 | Selective Insecticides Based on Substituted Cyclic Ketoenols and Safeners | KCNE1, CYCS, AKR1D1 | TDP1 4701/4885TSHR 3424/4885CYP3A4 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.