Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537595 | 0.87 | IDO1 (0.35) | IDO1TP53 | |
| SCHEMBL10536625 | 0.86 | TP53 (0.33) | IDO1TP53TSHRCYP3A4HSD17B10 | |
| SCHEMBL3164872 | 0.76 | TP53 (0.48) | IDO1TP53TSHRCYP3A4ALDH1A1 | |
| SCHEMBL9629038 | 0.73 | ALDH1A1 (0.52) | IDO1TP53TSHRCYP3A4ALDH1A1 | |
| SCHEMBL9227158 | 0.73 | CYP3A4 (0.41) | TP53TSHRCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL10539835 | 0.73 | HSD17B10 (0.50) | IDO1TP53TSHRCYP3A4ALDH1A1 | |
| SCHEMBL3054170 | 0.69 | — | — | |
| SCHEMBL29497656 | 0.69 | — | — | |
| SCHEMBL28682144 | 0.68 | TRPV4 (0.46) | TP53ALDH1A1LMNA | |
| SCHEMBL9223413 | 0.68 | FLT1 (0.40) | IDO1CYP3A4TDP1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810773-A | HIGH MOLECULAR WEIGHT ENGINEERING THERMOPLASTICS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0215312-A1 | Method for producing of polyarylene sulfides | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |