Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537455 | 0.78 | CA12 (0.56) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11580901 | 0.77 | MAOB (0.43) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL30485959 | 0.76 | SMN1; SMN2 (0.40) | TRPV4MEN1KMT2AALDH1A1SLC6A2 | |
| SCHEMBL29636402 | 0.73 | TRPV4 (0.55) | TRPV4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL2127233 | 0.73 | TRPV4 (0.55) | TRPV4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9227158 | 0.72 | CYP3A4 (0.41) | FLT1FLT4KDRALDH1A1TP53 | |
| SCHEMBL3164872 | 0.72 | TP53 (0.48) | ALDH1A1TP53LMNA | |
| SCHEMBL28298273 | 0.72 | TRPV4 (0.53) | TRPV4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL254432 | 0.72 | TRPV4 (0.53) | TRPV4MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL21327658 | 0.71 | TRPV4 (0.48) | TRPV4FLT1FLT4KDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912597-B | ROR gamma inhibitor, preparation method and medical application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113912597-A | ROR gamma inhibitor, preparation method and medical application thereof | 赛诺哈勃药业（成都）有限公司 | 2022-01-11 | — | — | CN | disclosed |