Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.83 |
| ▸ | HCAR3 | P49019 | 11/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118775 | 0.91 | MAPT (0.71) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL7570478 | 0.90 | MAPT (0.92) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL13043456 | 0.83 | MAPT (0.68) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL2688335 | 0.81 | HCAR3 (1.00) | MAPTHCAR3ALDH1A1MEN1KMT2A | |
| SCHEMBL27325723 | 0.80 | ALDH1A1 (0.81) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL22118774 | 0.79 | MAPT (0.55) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL22118777 | 0.79 | MAPT (0.54) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL14700356 | 0.79 | MAPT (0.61) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL5564368 | 0.78 | HCAR3 (0.63) | MAPTGAAHCAR3ALDH1A1MEN1 | |
| SCHEMBL11839922 | 0.78 | MAPT (0.75) | MAPTGAAHCAR3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806151-A | ESTERIFICATION, THEN AMINATION OF 4-CHLORO-3,5-DINITRO-BENZOIC ACID; ACID CATALYST, SALT FORMATION OF EXCESS; FUNGICIDES, HERBICIDES | BUDAPESTI VEGYIMUVEK (HU) | 1989-02-21 | — | — | US | disclosed |