Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983582 | 0.92 | FDFT1 (0.49) | FAAHTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL202774 | 0.84 | ALDH1A1 (0.54) | TSHRHSD17B10ALDH1A1KDM4ETDP1 | |
| SCHEMBL8088764 | 0.83 | SIGMAR1 (0.52) | FAAHTSHRHSD17B10ALDH1A1KDM4E | |
| Bromide SCHEMBL11317156 | 0.82 | ALDH1A1 (0.53) | TSHRHSD17B10ALDH1A1KDM4ETDP1 | |
| SCHEMBL16316303 | 0.78 | FDFT1 (0.50) | FAAHTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11705881 | 0.78 | TSHR (0.57) | TSHRHSD17B10ALDH1A1KDM4ETDP1 | |
| SCHEMBL9707070 | 0.78 | FFAR1 (0.59) | — | |
| SCHEMBL9558481 | 0.77 | FAAH (0.45) | FAAHALDH1A1KDM4ETDP1HTT | |
| SCHEMBL13802648 | 0.77 | FAAH (0.49) | FAAHTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4178681 | 0.77 | ALDH1A1 (0.51) | FAAHALDH1A1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876251-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |