Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 18/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.39 |
| ▸ | GABRP | O00591 | 7/20 | 0.39 |
| ▸ | GABRD | O14764 | 7/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.39 |
| ▸ | GABRE | P78334 | 7/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10542967 | 0.85 | MAPT (0.34) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7199555 | 0.80 | GABRA2 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL26584 | 0.80 | GABRA2 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9703996 | 0.76 | MAPT (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9703352 | 0.76 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10543951 | 0.76 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10546252 | 0.75 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9200285 | 0.74 | GABRP (0.45) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10543342 | 0.74 | MAPT (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10543236 | 0.74 | MAPT (0.39) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803215-A | 5-Heterocyclyl-1-aryl-pyrazoles, composition containing them, and method of using them to combat insects, acarids and nematodes | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-07 | — | — | US | claimed |