SCHEMBL26584

SCHEMBL26584

Nc1c([S+]([O-])C(F)(F)F)cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA2 P47869 20/20 0.51
GABRB2 P47870 20/20 0.51
GABRP O00591 19/20 0.51
GABRD O14764 19/20 0.51
GABRA1 P14867 19/20 0.51
GABRB1 P18505 19/20 0.51
GABRG2 P18507 19/20 0.51
GABRB3 P28472 19/20 0.51
GABRA5 P31644 19/20 0.51
GABRA3 P34903 19/20 0.51
GABRA4 P48169 19/20 0.51
GABRE P78334 19/20 0.51
GABRA6 Q16445 19/20 0.51
GABRG1 Q8N1C3 19/20 0.51
GABRG3 Q99928 19/20 0.51
GABRQ Q9UN88 19/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7199555 1.00 GABRA2 (0.51) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL7086725 0.92 GABRA2 (0.45) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL10582758 0.91 GABRA2 (0.47) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL10582418 0.85 GABRA2 (0.36) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL7086533 0.84 GABRA2 (0.38) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL7082496 0.84 GABRP (0.35) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL10542227 0.80 GABRB3 (0.39) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL10670241 0.80 GABRB3 (0.54) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL10630751 0.77 GABRA2 (0.51) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL8183755 0.77 GABRB3 (0.42) GABRA2GABRB2GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340495-B O-nitrobenzene compound and preparation method and application thereof 华东理工大学 2024-12-03 CN disclosed
CN-115340495-A O-nitrobenzene compound and preparation method and application thereof 华东理工大学 2022-11-15 CN disclosed
US-9375001-B1 Granular fly bait WELLMARK INTERNATIONAL (US) 2016-06-28 US disclosed
EP-2514316-A1 Pesticide composition BASF SE (DE) 2012-10-24 EP disclosed
EP-2235097-B1 INSECTICIDE-EQUIPPED PARTICLES MADE OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-EQUIPPED MOLDED PARTS WHICH CAN BE OBTAINED THEREFROM BASF SE (DE) 2011-11-30 EP disclosed
US-20110263585-A1 Screening Assay for Insecticides BASF SE (DE) 2011-10-27 US disclosed
US-20110237439-A1 Process for the Preparation of Random Radical Copolymers, and Active Substance Compositions Obtainable Therefrom BASF SE (DE) 2011-09-29 US disclosed
US-20110201662-A1 METHOD FOR PRODUCING XPS MOULDED PIECES PROVIDED WITH INSECTICIDE BASF SE (DE) 2011-08-18 US disclosed
EP-2355656-A2 METHOD FOR PRODUCING XPS MOULDED PIECES PROVIDED WITH INSECTICIDE BASF SE (DE) 2011-08-17 EP disclosed
US-20110098332-A1 Insecticides for Increasing the Crop Yield BASF SE (DE) 2011-04-28 US disclosed
EP-2230905-A2 PROCESS FOR THE PRODUCTION OF INSECTICIDE-MODIFIED BEAD MATERIAL COMPOSED OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-MODIFIED MOLDINGS OBTAINABLE THEREFROM BASF SE (DE) 2010-09-29 EP disclosed
WO-2010046379-A2 METHOD FOR PRODUCING XPS MOULDED PIECES PROVIDED WITH INSECTICIDE BASF SE (DE) 2010-04-29 WO disclosed
WO-2009080464-A2 PROCESS FOR THE PRODUCTION OF INSECTICIDE-MODIFIED BEAD MATERIAL COMPOSED OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-MODIFIED MOLDINGS OBTAINABLE THEREFROM BASF SE (DE) 2009-07-02 WO disclosed
WO-2009080487-A2 INSECTICIDE-MODIFIED BEAD MATERIAL COMPOSED OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-MODIFIED MOLDINGS OBTAINABLE THEREFROM BASF SE (DE) 2009-07-02 WO disclosed
WO-2009080723-A1 INSECTICIDE-EQUIPPED PARTICLES MADE OF EXPANDABLE POLYSTYRENE AND INSECTICIDE-EQUIPPED MOLDED PARTS WHICH CAN BE OBTAINED THEREFROM BASF SE (DE) 2009-07-02 WO disclosed
CN-1102832-C Method for controlling population of social insects with 1-arylpyrazoles or 1-heteroarylpyrazoles SCOTTS DE FRANCE (FR) 2003-03-12 CN disclosed
CN-1192653-A Method for controlling population of social insects with 1-arylpyrazoles or 1-heteroarylpyrazoles RHONE POULENC JARDIN (FR) 1998-09-09 CN disclosed
EP-0392241-B1 SUBSTITUTED 1-ARYLPYRAZOLS BAYER AG (DE) 1993-06-02 EP disclosed
US-4971989-A PESTICIDES, MITICIDES, INSECTICIDES AND NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-11-20 US disclosed
EP-0392241-A1 Substituted 1-Arylpyrazols BAYER AG (DE) 1990-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237439-A1 Process for the Preparation of Random Radical Copolymers, and Active Substance Compositions Obtainable Therefrom ALOX5, CHRM5, CHRM2 GABRA2 985/4885GABRB2 1130/4885GABRP 1002/4885
US-20110098332-A1 Insecticides for Increasing the Crop Yield GABBR1, GABBR2, GABARAPL2 GABRA2 14/4885GABRB2 6/4885GABRP 12/4885
US-20110263585-A1 Screening Assay for Insecticides DDT, OSBP2, CDS2 GABRA2 3434/4885GABRB2 2731/4885GABRP 1726/4885
US-20110201662-A1 METHOD FOR PRODUCING XPS MOULDED PIECES PROVIDED WITH INSECTICIDE CYP2F1, CYP4F3, CYP4F2 GABRA2 564/4885GABRB2 379/4885GABRP 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.