SCHEMBL1054288

SCHEMBL1054288

Nc1ccccc1/C=C/c1ccc2ccccc2c1/C=C/c1ccccc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.45
▸ TSHR P16473 2/20 0.45
▸ HSD17B10 Q99714 2/20 0.45
▸ CYP3A4 P08684 2/20 0.45
▸ HPGD P15428 1/20 0.45
▸ KEAP1 Q14145 1/20 0.45
▸ SENP2 Q9HC62 2/20 0.39
▸ SENP1 Q9P0U3 2/20 0.39
▸ SUMO2 P61956 1/20 0.39
▸ SUMO1 P63165 1/20 0.39
▸ SENP7 Q9BQF6 1/20 0.39
▸ SENP3 Q9H4L4 1/20 0.39
▸ HPRT1 P00492 2/20 0.39
▸ CYP2A6 P11509 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ CRHBP P24387 1/20 0.37
▸ CRHR2 Q13324 1/20 0.37
▸ CHAT P28329 4/20 0.37
▸ ERN1 O75460 1/20 0.37
▸ RRM1 P23921 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6422123 0.92 HPRT1 (0.47) ALDH1A1TSHRHSD17B10CYP3A4HPGD
SCHEMBL4947905 0.85 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10CYP3A4HPGD
SCHEMBL3932039 0.81 ALDH1A1 (0.58) ALDH1A1TSHRHSD17B10CYP3A4HPGD
SCHEMBL10890521 0.79 CYP19A1 (0.50) SENP7CHAT
SCHEMBL10890524 0.79 CYP19A1 (0.50) SENP7CHAT
SCHEMBL6483171 0.79 CHAT (0.50) ALDH1A1TSHRHSD17B10HPGDSENP7
SCHEMBL6422555 0.79 HPRT1 (0.52) ALDH1A1TSHRHSD17B10CYP3A4HPGD
SCHEMBL6494775 0.79 ERN1 (0.49) ALDH1A1TSHRHSD17B10CYP2A6TDP1
SCHEMBL6483174 0.79 CHAT (0.50) ALDH1A1TSHRHSD17B10HPGDSENP7
SCHEMBL6494777 0.79 ERN1 (0.49) ALDH1A1TSHRHSD17B10CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1092704-B1 Bis (aminostyryl) naphtalene compounds, synthesis intermediates thereof, and process for production thereof SONY CORP (JP) 2006-03-08 — — EP claimed
US-6897341-B2 Bis(aminostyryl)naphthalene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2005-05-24 — — US claimed
US-20030220523-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof JOLED INC. (JP) 2003-11-27 — — US claimed
US-20030212289-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof JOLED INC. (JP) 2003-11-13 — — US claimed
US-20030204115-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof JOLED INC. (JP) 2003-10-30 — — US claimed
US-20030073867-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof JOLED INC. (JP) 2003-04-17 — — US claimed
US-20030069448-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for producion thereof JOLED INC. (JP) 2003-04-10 — — US claimed
US-6492557-B1 A BIS(AMINOSTYRYL)NAPHTHALENE COMPOUND REPRESENTED BY THE FORMULA (6) BELOW. THE COMPOUND OF THE PRESENT INVENTION EMITS INTENSE YELLOW TO RED LIGHT DEPENDING ON THE SUBSTITUENT GROUPS INTRODUCED THEREIN. THEREFORE, IT IS ORGANIC LIGHT SONY CORPORATION (JP) 2002-12-10 — — US claimed
EP-1092704-A2 Bis (aminostyryl) naphtalene compounds, synthesis intermediates thereof, and process for production thereof SONY CORPORATION (JP) 2001-04-18 — — EP claimed
EP-1662844-B1 ORGANIC EL DEVICE AND DISPLAY SONY CORP (JP) 2012-07-18 — — EP disclosed
US-8067885-B2 Organic EL device and display SONY CORPORATION (JP) 2011-11-29 — — US disclosed
US-7863808-B2 Resonant cavity color conversion EL device and organic EL display device using the same FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2011-01-04 — — US disclosed
US-20090212696-A1 Resonant cavity color conversion el device and organic el display device using the same FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2009-08-27 — — US disclosed
US-20080003455-A1 Organic El Device FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2008-01-03 — — US disclosed
US-6492557-B1 A BIS(AMINOSTYRYL)NAPHTHALENE COMPOUND REPRESENTED BY THE FORMULA (6) BELOW. THE COMPOUND OF THE PRESENT INVENTION EMITS INTENSE YELLOW TO RED LIGHT DEPENDING ON THE SUBSTITUENT GROUPS INTRODUCED THEREIN. THEREFORE, IT IS ORGANIC LIGHT SONY CORPORATION (JP) 2002-12-10 — — US disclosed
US-6492557-B1 A BIS(AMINOSTYRYL)NAPHTHALENE COMPOUND REPRESENTED BY THE FORMULA (6) BELOW. THE COMPOUND OF THE PRESENT INVENTION EMITS INTENSE YELLOW TO RED LIGHT DEPENDING ON THE SUBSTITUENT GROUPS INTRODUCED THEREIN. THEREFORE, IT IS ORGANIC LIGHT SONY CORPORATION (JP) 2002-12-10 — — US disclosed
EP-1092704-A3 Bis (aminostyryl) naphtalene compounds, synthesis intermediates thereof, and process for production thereof SONY CORPORATION (JP) 2001-04-25 — — EP disclosed
EP-1092704-A2 Bis (aminostyryl) naphtalene compounds, synthesis intermediates thereof, and process for production thereof SONY CORPORATION (JP) 2001-04-18 — — EP disclosed
EP-1092704-A2 Bis (aminostyryl) naphtalene compounds, synthesis intermediates thereof, and process for production thereof SONY CORPORATION (JP) 2001-04-18 — — EP disclosed
JP-2001106658-A BIS(AMINOSTYRYL)NAPHTHALENE COMPOUND AND ITS SYNTHETIC INTERMEDIATE, AND THEIR PRODUCTION SONY CORP 2001-04-17 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069448-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for producion thereof DHPS, DDC, AASDHPPT ALDH1A1 554/4885TSHR 4794/4885HSD17B10 1485/4885
US-20030220523-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof DDC, DHPS, ALDH7A1 ALDH1A1 556/4885TSHR 4760/4885HSD17B10 1619/4885
US-20030204115-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof DDC, DHPS, ALDH7A1 ALDH1A1 492/4885TSHR 4750/4885HSD17B10 1346/4885
US-20030073867-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof DDC, DHPS, AASDHPPT ALDH1A1 584/4885TSHR 4790/4885HSD17B10 1763/4885
US-20030212289-A1 Bis (aminostyryl) naphthalene compound, synthesis intermediate thereof, and process for production thereof DDC, DHPS, ALDH7A1 ALDH1A1 492/4885TSHR 4750/4885HSD17B10 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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