Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545517 | 0.89 | ALDH1A1 (0.37) | HTTALDH1A1RAB9ACTSSL3MBTL1 | |
| SCHEMBL8626971 | 0.87 | POLB (0.38) | HTTALDH1A1CTSSL3MBTL1KMT2A | |
| SCHEMBL10541118 | 0.86 | PKM (0.39) | ALDH1A1KMT2AMEN1OPRK1 | |
| SCHEMBL10547320 | 0.85 | PKM (0.41) | ALDH1A1KMT2AMEN1OPRK1 | |
| SCHEMBL10545030 | 0.85 | PKM (0.41) | ALDH1A1KMT2AMEN1OPRK1 | |
| SCHEMBL8622094 | 0.79 | MEN1 (0.38) | HTTALDH1A1RAB9ACTSSEPHX2 | |
| SCHEMBL8082394 | 0.79 | CHRM1 (0.36) | HTTALDH1A1RAB9ACTSSEPHX2 | |
| SCHEMBL8625044 | 0.77 | GPBAR1 (0.37) | CTSSCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10546411 | 0.77 | KMT2A (0.41) | KMT2ANPC1MEN1 | |
| SCHEMBL10546517 | 0.76 | HDAC1 (0.35) | CTSSEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822788-A | MICROBIOCIDES, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4822790-A | ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4725591-A | USED WITH AMINO ACID DERIVATIVE ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0095764-B1 | 2-OXOAZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4684724-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-04 | — | — | US | disclosed |
| US-4675397-A | MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-06-23 | — | — | US | disclosed |
| US-4665067-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0083039-B1 | 4-CYANO-2-AZETIDINONES AND PRODUCTION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1986-03-19 | — | — | EP | disclosed |
| US-4560508-A | BETA-LACTAMASE INHIBITORS, ANINICROBIAL AGENT, CHEMICAL INTERMEDIATE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| US-4550105-A | BETA-LACTAMASE INHIBITORS, ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0053815-B1 | 2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-05-08 | — | — | EP | disclosed |
| EP-0095764-A2 | 2-Oxoazetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-12-07 | — | — | EP | disclosed |
| EP-0053815-A1 | 2-Oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
| EP-0021676-A1 | 3-Methoxy-2-oxoazetidine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |