Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MTR | Q99707 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543810 | 0.94 | CNR1 (0.37) | CTSSLMNAIL4I1 | |
| SCHEMBL8622094 | 0.80 | MEN1 (0.38) | CTSSPOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL8626971 | 0.78 | POLB (0.38) | CTSSPOLBIDH1MEN1KMT2A | |
| SCHEMBL10546806 | 0.77 | HTT (0.43) | CTSSCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL8077395 | 0.77 | KMT2A (0.38) | CTSSPOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL8623693 | 0.77 | ALDH1A1 (0.46) | POLBCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL8082394 | 0.77 | CHRM1 (0.36) | CTSSPOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL10545517 | 0.76 | ALDH1A1 (0.37) | TP53CTSSPOLBCACNA2D1CACNA1B | |
| SCHEMBL10645319 | 0.75 | TSHR (0.39) | LMNAMEN1KMT2ACCKBRIL4I1 | |
| SCHEMBL10645325 | 0.75 | HTT (0.40) | TP53POLBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503597-B1 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KK (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5599925-A | BACTERICIDES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |