Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553934 | 0.86 | MAOA (0.53) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL10549283 | 0.81 | ADORA3 (0.48) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL3215517 | 0.80 | PTGER1 (0.47) | SMN1; SMN2NPC1ALDH1A1SLC6A4 | |
| SCHEMBL10695473 | 0.80 | MAPT (0.52) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL23073217 | 0.78 | MAOA (0.56) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL10547117 | 0.78 | MAOA (0.55) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL10548938 | 0.78 | KDM4E (0.47) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL3223985 | 0.77 | ALDH1A1 (0.41) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL3212340 | 0.77 | PTGS2 (0.44) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL18152742 | 0.76 | MAOA (0.56) | MAOAMAOBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |