Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414817 | 0.85 | ALDH1A1 (0.37) | ALDH1A1PKMLMNAPTGS2SLC22A6 | |
| SCHEMBL10544583 | 0.81 | ALDH1A1 (0.37) | ALDH1A1PKMEGFRMAPTKMT2A | |
| SCHEMBL10544574 | 0.81 | ALDH1A1 (0.37) | ALDH1A1PKMEGFRMAPTKMT2A | |
| SCHEMBL10547616 | 0.80 | GAPDH (0.40) | ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL10548246 | 0.80 | GAPDH (0.40) | ALDH1A1PKMKMT2AKDM4E | |
| SCHEMBL10549582 | 0.78 | POLB (0.53) | ALDH1A1PKMLMNAMAPTHSD17B10 | |
| SCHEMBL10544809 | 0.78 | PKM (0.35) | ALDH1A1PKMLMNAMAPTHSD17B10 | |
| SCHEMBL10550552 | 0.78 | NPC1 (0.41) | ALDH1A1HSD17B10KMT2AL3MBTL1 | |
| SCHEMBL10544819 | 0.78 | PKM (0.35) | ALDH1A1PKMLMNAMAPTHSD17B10 | |
| SCHEMBL10551027 | 0.76 | KDM4E (0.34) | ALDH1A1LMNAMAPTHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831130-A | β-lactam antibacterial agents | HOFFMANN-LA ROCHE INC. (US) | 1989-05-16 | — | — | US | disclosed |