Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546822 | 0.85 | CRHBP (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL10544184 | 0.84 | TTR (0.41) | TTRDPP4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10547910 | 0.84 | L3MBTL1 (0.45) | KMT2AMEN1LMNAGAAALDH1A1 | |
| SCHEMBL10549664 | 0.83 | ALDH1A1 (0.46) | CYP1A2CYP3A4LMNAALDH1A1MAPT | |
| SCHEMBL10547615 | 0.81 | TTR (0.41) | TTRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10546981 | 0.81 | TTR (0.44) | TTRCYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL10547895 | 0.81 | TTR (0.41) | TTRDPP4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8187061 | 0.79 | TTR (0.64) | TTRDPP4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10544839 | 0.78 | AR (0.39) | TTRCYP3A4KMT2AMEN1GAA | |
| SCHEMBL10973887 | 0.76 | LTA4H (0.50) | KMT2AMEN1LMNAALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |