Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 8/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7322286 | 0.99 | KDM4E (0.40) | KDM4ESLC9A1HSD17B1HSD17B2ESR1 | |
| Hydrochloric Acid SCHEMBL7325678 | 0.85 | KDM4E (0.40) | KDM4ESLC9A1LMNAALDH1A1PRNP | |
| Hydrochloric Acid SCHEMBL7318923 | 0.82 | PDE4A (0.46) | KDM4ESLC9A1ALDH1A1KCNH2 | |
| SCHEMBL7318508 | 0.80 | AR (0.40) | KDM4ESLC9A1LMNAALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL7323889 | 0.79 | AR (0.40) | KDM4ESLC9A1LMNAALDH1A1KCNH2 | |
| SCHEMBL10092622 | 0.77 | ALDH1A1 (0.55) | KDM4ESLC9A1LMNAALDH1A1PRNP | |
| SCHEMBL10550285 | 0.76 | KDM4E (0.44) | KDM4ESLC9A1HSD17B1HSD17B2ESR1 | |
| Hydrochloric Acid SCHEMBL7329120 | 0.76 | SLC9A1 (0.65) | KDM4ESLC9A1ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7322278 | 0.75 | KDM4E (0.43) | KDM4ESLC9A1HSD17B1HSD17B2ESR1 | |
| Hydrochloric Acid SCHEMBL7320013 | 0.75 | SLC9A1 (0.45) | KDM4ESLC9A1LMNAALDH1A1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882354-A | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-11-21 | — | — | US | disclosed |