Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105209 | 0.80 | ADRA2A (0.38) | SLC6A2ADRA1A | |
| Medetomidine SCHEMBL26432 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| Dexmedetomidine SCHEMBL14861666 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| Dexmedetomidine SCHEMBL29431568 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| Medetomidine SCHEMBL787913 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| SCHEMBL5801661 | 0.75 | LMNA (0.32) | LMNATRPA1 | |
| Dexmedetomidine SCHEMBL12092460 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| Medetomidine SCHEMBL18497244 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| Dexmedetomidine SCHEMBL119382 | 0.75 | ADRA2A (0.50) | TRPA1SLC6A2ADRA1A | |
| SCHEMBL7252662 | 0.75 | MAPT (0.39) | LMNAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108872431-B | Method for detecting 4- (1- (2, 5-dimethylphenyl) ethyl) -1H-imidazole or/and hydrochloride thereof | 成都倍特药业股份有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-108872431-B | Method for detecting 4- (1- (2, 5-dimethylphenyl) ethyl) -1H-imidazole or/and hydrochloride thereof | 成都倍特药业股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-108872431-B | Method for detecting 4- (1- (2, 5-dimethylphenyl) ethyl) -1H-imidazole or/and hydrochloride thereof | 成都倍特药业股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-108872431-B | Method for detecting 4- (1- (2, 5-dimethylphenyl) ethyl) -1H-imidazole or/and hydrochloride thereof | 成都倍特药业股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| US-4826864-A | Substituted imidazole derivatives useful as antihypertensive or antithromtic agent or divretic | FARMOS GROUP LTD. (FI) | 1989-05-02 | — | — | US | disclosed |
| US-4639464-A | Antihypertensive substituted imidazole derivatives | FARMOS GROUP, LTD. (FI) | 1987-01-27 | — | — | US | disclosed |
| EP-0072615-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1985-12-27 | — | — | EP | disclosed |
| US-4544664-A | Antihypertensive substituted imidazole derivatives | FARMOS GROUP, LTD. (FI) | 1985-10-01 | — | — | US | disclosed |
| EP-0072615-A1 | Substituted imidazole derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-02-23 | — | — | EP | disclosed |