Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677823 | 0.84 | ALDH1A1 (0.39) | KDM4EALDH1A1ALDH3A1ALDH1A3HCAR3 | |
| SCHEMBL6451691 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL934755 | 0.77 | KCNH2 (0.51) | KDM4EALDH1A1ALDH3A1ALDH1A3L3MBTL1 | |
| SCHEMBL30592797 | 0.77 | KCNH2 (0.51) | KDM4EALDH1A1ALDH3A1ALDH1A3L3MBTL1 | |
| SCHEMBL10686148 | 0.76 | RAB9A (0.44) | KDM4EALDH1A1HCAR3CYP2A6MAPT | |
| SCHEMBL24042392 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1ALDH3A1ALDH1A3L3MBTL1 | |
| SCHEMBL19330155 | 0.74 | ALDH1A1 (0.57) | KDM4EALDH1A1ALDH3A1ALDH1A3HCAR3 | |
| SCHEMBL30369918 | 0.74 | ALDH1A1 (0.57) | KDM4EALDH1A1ALDH3A1ALDH1A3HCAR3 | |
| SCHEMBL3514121 | 0.73 | HCAR3 (0.35) | KDM4EALDH1A1ALDH3A1ALDH1A3HCAR3 | |
| SCHEMBL20810910 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1ALDH3A1ALDH1A3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847251-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-11 | — | — | US | disclosed |