Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550563 | 0.85 | GAA (0.50) | CYP2C19ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL10547539 | 0.80 | NR4A2 (0.44) | ALDH1A1TSHRKMT2AKDM4EMAPT | |
| SCHEMBL3965291 | 0.79 | KMT2A (0.44) | SLC6A3ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL8755551 | 0.77 | TSHR (0.61) | SLC6A3ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL68630 | 0.77 | LMNA (0.50) | ALDH1A1TSHRKMT2AKDM4EMAPT | |
| SCHEMBL28853940 | 0.77 | NR4A2 (0.42) | CYP2C19SLC6A3ALDH1A1TSHRKMT2A | |
| SCHEMBL8344887 | 0.77 | CYP2C19 (0.49) | CYP2C19EYA3ALDH1A1KMT2AMEN1 | |
| SCHEMBL8876044 | 0.77 | MAPT (0.42) | SLC6A3ALDH1A1TSHRKMT2ACYP2C9 | |
| SCHEMBL2950918 | 0.75 | TSHR (0.53) | CYP2C19SLC6A3ALDH1A1TSHRKMT2A | |
| Aniline SCHEMBL3829674 | 0.74 | ALDH1A1 (0.51) | SLC6A3ALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |