Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875450 | 0.89 | CDC25B (0.48) | MAPTNPC1TSHRALDH1A1KDM4E | |
| SCHEMBL8877391 | 0.87 | AKR1C3 (0.42) | MAPTTHRBRXFP1KMT2ANPC1 | |
| SCHEMBL8876122 | 0.78 | MTNR1A (0.43) | MAPTKMT2ANPC1RAB9ATSHR | |
| SCHEMBL10550378 | 0.77 | CYP2C19 (0.48) | MAPTTHRBSLC6A3KMT2ANPC1 | |
| SCHEMBL68630 | 0.73 | LMNA (0.50) | MAPTKMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL28434302 | 0.73 | SLC6A3 (0.49) | MAPTSLC6A3KMT2ATSHRALDH1A1 | |
| SCHEMBL28551648 | 0.72 | TSHR (0.50) | MAPTSLC6A3KMT2ATSHRALDH1A1 | |
| Aniline SCHEMBL3829674 | 0.71 | ALDH1A1 (0.51) | MAPTSLC6A3KMT2ATSHRALDH1A1 | |
| SCHEMBL8755551 | 0.70 | TSHR (0.61) | MAPTTHRBSLC6A3KMT2ARAB9A | |
| SCHEMBL22481057 | 0.70 | LMNA (0.53) | MAPTSLC6A3KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605896-A | Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1997-02-25 | — | — | US | disclosed |