Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550378 | 0.85 | CYP2C19 (0.48) | GAAMAPTALDH1A1LMNATP53 | |
| SCHEMBL10547539 | 0.83 | NR4A2 (0.44) | MAPTALDH1A1LMNANR4A2TSHR | |
| SCHEMBL3965291 | 0.82 | KMT2A (0.44) | MAPTALDH1A1LMNANR4A2TSHR | |
| SCHEMBL68630 | 0.81 | LMNA (0.50) | MAPTALDH1A1LMNANR4A2TSHR | |
| SCHEMBL28853940 | 0.81 | NR4A2 (0.42) | MAPTALDH1A1LMNANR4A2TSHR | |
| SCHEMBL7832336 | 0.75 | GAA (0.55) | GAAMAPTALDH1A1LMNATP53 | |
| SCHEMBL7823819 | 0.75 | GPR35 (0.53) | GAAMAPTALDH1A1LMNATP53 | |
| SCHEMBL516174 | 0.74 | KDM4E (0.53) | ALDH1A1LMNATSHRKMT2ANPC1 | |
| SCHEMBL3967537 | 0.72 | GAA (0.41) | GAAMAPTALDH1A1LMNATP53 | |
| Aniline SCHEMBL3829674 | 0.72 | ALDH1A1 (0.51) | GAAMAPTALDH1A1LMNANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |