Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.43 |
| ▸ | FEN1 | P39748 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 10/20 | 0.40 |
| ▸ | CA1 | P00915 | 9/20 | 0.40 |
| ▸ | CA9 | Q16790 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA6 | P23280 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828659 | 0.75 | CA2 (0.41) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL1080972 | 0.73 | CA2 (0.61) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL8347239 | 0.71 | CA2 (0.58) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL7044580 | 0.71 | PTGS2 (0.41) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL31105556 | 0.71 | PTGS2 (0.41) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL29967288 | 0.70 | EDNRA (0.49) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL1667127 | 0.70 | EDNRA (0.49) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL10553102 | 0.70 | ALOX5AP (0.43) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL4669011 | 0.70 | ALOX5AP (0.49) | ALOX5APFEN1CA2CA1CA9 | |
| SCHEMBL15511770 | 0.70 | BCAT2 (0.53) | ALOX5APFEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810282-A | 3-ORTHO-(ISOXAZOLYL,ISOTHIAZOLYL, PYRAZOLYL,THIADIAZOLYL, OXADIAZOLYL AND TRIAZOLYL BENZENESULFONUREYLENE-1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0083975-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4695311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| US-4606755-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
| US-4511392-A | N--/PYRIMIDIN-2-YLAMINOCARBENYL/-HETERO-SUBSTITUETED BENZENSESULFO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-16 | — | — | US | disclosed |