Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.40 |
| ▸ | FEN1 | P39748 | 5/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491067 | 0.79 | CA2 (0.34) | CA2CA1CA9CA6CA12 | |
| SCHEMBL28869430 | 0.79 | NPC1 (0.41) | CA2CA1CA9CA12CA4 | |
| SCHEMBL27536398 | 0.78 | BRD4 (0.31) | — | |
| SCHEMBL4059082 | 0.77 | MDM2 (0.41) | CYP2C9 | |
| SCHEMBL23235485 | 0.76 | MDM2 (0.38) | CA2CA1CA9STAT3 | |
| SCHEMBL10550462 | 0.75 | ALOX5AP (0.43) | CA2CA1CA9CA6CA12 | |
| SCHEMBL1080972 | 0.74 | CA2 (0.61) | CA2CA1CA9CA6CA12 | |
| Thiophene SCHEMBL27619739 | 0.72 | CA1 (0.38) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8347239 | 0.72 | CA2 (0.58) | CA2CA1CA9CA6CA12 | |
| SCHEMBL8890179 | 0.72 | PTPRC (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110521729-A | A kind of composition pesticide and its application | HEBEI ZHONGTIANBANGZHENG BIOLOGIC SCIENCE CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-105358132-B | Abuse resistant capsules | R.P.谢勒技术有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-107232207-A | A kind of herbicidal composition containing ring sulphur ketone, Garagard and isoxadifen | 河南传奇农业科技有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-106818826-A | A kind of crop phytocide composition | 安徽常泰化工有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-103633062-B | Compound semiconductor integrated circuit | 稳懋半导体股份有限公司 | 2016-11-02 | — | — | CN | claimed |
| US-20030069287-A1 | Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors | PHARMACIA CORPORATION | 2003-04-10 | — | — | US | claimed |
| EP-1288206-A1 | Substituted benzenesulfonamide derivatives as prodrugs of COX-2 inhibitors | G.D. SEARLE & CO. (US) | 2003-03-05 | — | — | EP | claimed |
| US-6436967-B1 | PREFERENTIAL CYCLOOXYGENASE INHIBITORS USED AS INJECTABLE ANALGESIC AND ANTIINFLAMMATORY AGENTS HAVING REDUCED SIDE EFFECTS; ACYLATION | PHARMACIA CORPORATION | 2002-08-20 | — | — | US | claimed |
| CN-106689202-B | A kind of bactericidal composition | 江苏龙灯化学有限公司 | 2019-11-22 | — | — | CN | disclosed |
| CN-209656599-U | A kind of flash detecting device | SHENZHEN FURUIKANG TECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-209656600-U | A kind of flash detecting device | SHENZHEN FURUIKANG TECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-209656598-U | A kind of flash detecting device and X-ray excited polycrystalline structure scintillator | SHENZHEN FURUIKANG TECH CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-209570532-U | A kind of objective table driving assembly and detection device | SHENZHEN FURUIKANG TECH CO LTD | 2019-11-01 | — | — | CN | disclosed |
| CN-209570534-U | A kind of darkroom component and detection device | SHENZHEN FURUIKANG TECH CO LTD | 2019-11-01 | — | — | CN | disclosed |
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0870764-A1 | Sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| CN-1175411-A | Use of dicafeoyl quininic acid in treatment of hepatitis B and diseases associated with retrovirus and cafeoyl quininic acid derivs. | RADIOLOGY INST MILITARY MEDICA (CN) | 1998-03-11 | — | — | CN | disclosed |
| US-5571821-A | CARDIOVASCULAR DISORDERS TO MODULATE ENDOTHELIN, HYPOTENSIVE AGENTS AND VASOCONSTRICTION | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0699191-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027979-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | IMMUNOPHARMACEUTICS, INC. (US) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069287-A1 | Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors | PTGS2, PTGES2, PTGES | CA2 920/4885CA1 2057/4885CA9 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.