Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554155 | 0.86 | GLRA3 (0.50) | GABRA1GABRB1SMN1; SMN2NPSR1GAA | |
| SCHEMBL20099506 | 0.85 | GABRA1 (0.42) | GABRA1GABRB1SMN1; SMN2NPSR1GAA | |
| SCHEMBL47718 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1GAALMNARECQL | |
| SCHEMBL2341096 | 0.83 | GABRA1 (0.58) | GABRA1GABRB1GAALMNAALDH1A1 | |
| SCHEMBL11699535 | 0.83 | SMN1; SMN2 (0.43) | GABRA1GABRB1SMN1; SMN2NPSR1GAA | |
| SCHEMBL25760420 | 0.81 | LMNA (0.42) | GABRA1GABRB1SMN1; SMN2NPSR1GAA | |
| Acetic Acid SCHEMBL1928603 | 0.80 | GABRA1 (0.59) | GABRA1GABRB1GAALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11652316 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1GAALMNARECQL | |
| Hydrochloric Acid SCHEMBL11652321 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1GAALMNARECQL | |
| SCHEMBL11611475 | 0.79 | CA12 (0.49) | GABRA1GABRB1SMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11684590-B2 | Substituted alkylphenols as HCN1 antagonists | CORNELL UNIVERSITY (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11684590-B2 | Substituted alkylphenols as HCN1 antagonists | HCN1, HCN2, HCN3 | GABRA1 423/4885GABRB1 312/4885SMN1; SMN2 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.