Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721145 | 0.92 | NR4A2 (0.51) | NR4A2MAOBALDH1A1FFAR1FFAR4 | |
| SCHEMBL10566317 | 0.89 | FFAR4 (0.52) | NR4A2MAOBFFAR1FFAR4PPARA | |
| SCHEMBL1918298 | 0.88 | NR4A2 (0.49) | NR4A2MAOBALDH1A1GAAKDM4C | |
| SCHEMBL13939923 | 0.88 | RAB9A (0.59) | NR4A2MAOBALDH1A1GAAKDM4C | |
| SCHEMBL9845266 | 0.81 | NR4A2 (0.56) | NR4A2NPC1RAB9A | |
| SCHEMBL3977944 | 0.79 | NR4A2 (0.58) | NR4A2MAOBKDM4CFFAR1FFAR4 | |
| SCHEMBL28605553 | 0.78 | PARP10 (0.49) | MAOBALDH1A1GAAFFAR1FFAR4 | |
| SCHEMBL16429122 | 0.77 | KEAP1 (0.52) | ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL10565772 | 0.77 | RXRA (0.51) | NR4A2MAOBFFAR1FFAR4PPARA | |
| SCHEMBL4420072 | 0.77 | NR4A2 (0.59) | NR4A2MAOBFFAR1PPARAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |