SCHEMBL10554307

SCHEMBL10554307

C=CCCc1cccc(C(C)(C)C)c1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
ALOX12 P18054 1/20 0.46
GABRA1 P14867 3/20 0.46
GABRB2 P47870 3/20 0.46
ATM Q13315 1/20 0.42
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
HSPA5 P11021 2/20 0.35
IAPP P10997 4/20 0.35
GAA P10253 2/20 0.35
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1980875 0.83 GABRA1 (0.59) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL3809080 0.79 CA2 (0.59) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL7065972 0.79 CA2 (0.59) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL23925732 0.77 ALDH1A1 (0.46) CA2GABRA1GABRB2ALDH1A1IAPP
SCHEMBL430927 0.77 CA2 (0.57) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL2935552 0.76 CA2 (0.67) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL57139 0.76 GABRA1 (0.67) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL6567771 0.76 CA2 (0.55) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL2208339 0.76 CA2 (0.55) CA2ALOX12GABRA1GABRB2ATM
SCHEMBL6567369 0.75 CA2 (0.53) CA2ALOX12GABRA1GABRB2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4847303-A UNSATURATED KETONES THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US disclosed