Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23842558 | 0.91 | GABRA1 (0.69) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL9752003 | 0.91 | HSPA5 (0.57) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL18468286 | 0.89 | CA2 (0.53) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL57139 | 0.87 | GABRA1 (0.67) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL9514064 | 0.87 | CA2 (0.55) | CA2GABRA1GABRB2HSPA5ATM | |
| SCHEMBL12733244 | 0.86 | HSPA5 (0.77) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL30578552 | 0.86 | HSPA5 (0.53) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL10495890 | 0.85 | CA2 (0.53) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL9817051 | 0.85 | CA2 (0.59) | CA2GABRA1GABRB2HSPA5CYP2C9 | |
| SCHEMBL10706992 | 0.85 | CA2 (0.64) | CA2GABRA1GABRB2HSPA5CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2023884-B1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2017-03-22 | — | — | EP | claimed |
| EP-2476404-B1 | Method, means and kit for infiltrating enamel lesions | CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2017-03-22 | — | — | EP | claimed |
| US-8853297-B2 | Method and means for infiltrating enamel lesions | CHARITE UNIVERSITATSMEDIZIN BERLIN (DE) | 2014-10-07 | — | — | US | claimed |
| EP-2476404-A1 | Method, means and kit for infiltrating enamel lesions | Charité Universitätsmedizin Berlin (DE) | 2012-07-18 | — | — | EP | claimed |
| EP-1854445-B1 | Method and means for infiltrating enamel lesions | CHARITE UNIVERSITAETSMEDIZIN (DE) | 2010-09-15 | — | — | EP | claimed |
| US-20090304622-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) | 2009-12-10 | — | — | US | claimed |
| EP-2023884-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | Ernst Mühlbauer GmbH & Co.KG (DE) | 2009-02-18 | — | — | EP | claimed |
| US-7485673-B2 | Method of infiltrating enamel lesions | CHARITE-UNIVERSITATSMEDIZIN BERLINE (DE) | 2009-02-03 | — | — | US | claimed |
| WO-2007131725-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2007-11-22 | — | — | WO | claimed |
| EP-1854445-A1 | Method and means for infiltrating enamel lesions | Charite-Universitätsmedizin Berlin (DE) | 2007-11-14 | — | — | EP | claimed |
| US-20060264532-A1 | Method of infiltrating enamel lesions | CHARITE - UNIVERSITATSMEDIZIN BERLIN (DE) | 2006-11-23 | — | — | US | claimed |
| US-20060167129-A1 | Method of infiltrating enamel lesions | CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) | 2006-07-27 | — | — | US | claimed |
| WO-2003043935-A1 | OXIDATION RESISTANT GRANULAR ACTIVATED CARBON | ENVIROTROL, INC. (US) | 2003-05-30 | — | — | WO | claimed |
| US-6425941-B1 | REMOVAL SOLVENTS | ENVIROTROL, INC. | 2002-07-30 | — | — | US | claimed |
| US-20210317065-A1 | Method for Purifying Polymerizable Fluoromonomer by Distillation | CENTRAL GLASS COMPANY, LIMITED (JP) | 2021-10-14 | — | — | US | disclosed |
| EP-3363856-B1 | RUBBER COMPOSITION | SUMITOMO RUBBER IND (JP) | 2020-05-20 | — | — | EP | disclosed |
| US-10414909-B2 | Rubber composition | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-09-17 | — | — | US | disclosed |
| US-3991139-A | NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-11-09 | — | — | US | disclosed |
| US-3985621-A | CYCLOHEXYLAMINOPROPANESULFONIC ACID | SANKYO COMPANY LIMITED (JA) | 1976-10-12 | — | — | US | disclosed |
| US-3972854-A | ANTIOXIDANT | PHILLIPS PETROLEUM COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317065-A1 | Method for Purifying Polymerizable Fluoromonomer by Distillation | AFF1, AFF4, AFF2 | CA2 3497/4885GABRA1 2165/4885GABRB2 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.