Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 4/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10554399 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| SCHEMBL9539081 | 0.98 | SLC6A2 (0.51) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| Oxalic Acid SCHEMBL9538009 | 0.87 | PLD2 (0.47) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| Oxalic Acid SCHEMBL9538011 | 0.87 | PLD2 (0.47) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| SCHEMBL9536266 | 0.86 | OPRK1 (0.51) | SLC6A2SLC6A4POLBSSTR5CYP2D6 | |
| SCHEMBL9536186 | 0.86 | MAPT (0.56) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| Oxalic Acid SCHEMBL9537867 | 0.85 | POLB (0.46) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| Oxalic Acid SCHEMBL9537860 | 0.85 | POLB (0.46) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| Oxalic Acid SCHEMBL9540591 | 0.85 | ALDH1A1 (0.53) | SLC6A2SLC6A4POLBCCR3SSTR5 | |
| SCHEMBL9535926 | 0.85 | SLC6A2 (0.51) | SLC6A2SLC6A4POLBCCR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839374-A | TREATING ALLERGIES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1989-06-13 | — | — | US | disclosed |