Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9144282 | 0.95 | FKBP1A (0.44) | CNR2FDFT1CYP24A1PTGESALOX5 | |
| SCHEMBL7028389 | 0.91 | CNR2 (0.50) | CNR2CYP24A1PSMD10 | |
| SCHEMBL18934371 | 0.90 | ALDH1A1 (0.47) | CNR2FDFT1PSMD10 | |
| SCHEMBL2567795 | 0.90 | ALDH1A1 (0.47) | CNR2FDFT1PSMD10 | |
| SCHEMBL2310681 | 0.87 | FKBP1A (0.51) | CNR2CYP24A1 | |
| SCHEMBL8484841 | 0.86 | FKBP1A (0.50) | CNR2CYP24A1 | |
| SCHEMBL8483790 | 0.86 | FKBP1A (0.50) | CNR2CYP24A1 | |
| SCHEMBL7459364 | 0.86 | FKBP1A (0.50) | CNR2CYP24A1 | |
| SCHEMBL10375119 | 0.86 | FKBP1A (0.50) | CNR2CYP24A1 | |
| SCHEMBL6586284 | 0.86 | FKBP1A (0.50) | CNR2CYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880800-A | PROSTAGLANDIN DERIVATIVES FOR ANTICOAGULANTS, VASODILATION, BRONCHODILATION | GLAXO GROUP LIMITED (GB) | 1989-11-14 | — | — | US | disclosed |
| US-4342756-A | AS ANTITHROMBOTIC AGENTS AND ANTIASTHMATIC AGENTS | GLAXO GROUP LIMITED (GB) | 1982-08-03 | — | — | US | disclosed |