SCHEMBL2567795

SCHEMBL2567795

Cc1ccc(CCCOS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
PSMD10 O75832 1/20 0.46
NPC1 O15118 1/20 0.45
CNR2 P34972 2/20 0.43
CA2 P00918 3/20 0.43
CA1 P00915 3/20 0.43
CA9 Q16790 3/20 0.43
FKBP1A P62942 3/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CA12 O43570 2/20 0.42
KCNH2 Q12809 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
APOBEC3A P31941 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18934371 1.00 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL18926560 0.95 GAA (0.50) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL18926554 0.94 CA2 (0.53) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL7723972 0.92 CNR2 (0.54) ALDH1A1KMT2AMEN1CYP2C9CYP2C19
SCHEMBL4793354 0.92 FKBP1A (0.52) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL7028389 0.92 CNR2 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19PSMD10
SCHEMBL8780852 0.91 FKBP1A (0.53) ALDH1A1KMT2APSMD10CNR2FKBP1A
SCHEMBL13649253 0.91 ENPP1 (0.52) ALDH1A1KMT2AMEN1CA2CA1
SCHEMBL11204014 0.90 BCHE (0.51) ALDH1A1KMT2AMEN1PSMD10CA2
SCHEMBL10557145 0.90 CNR2 (0.46) PSMD10CNR2FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561585-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS FOR USE IN THE TREATMENT, INHIBITION OF PROGRESSION, AND PREVENTION OF ECTOPIC CALCIFICATION Sanifit Therapeutics S.A. (ES) 2025-06-04 EP disclosed
US-20240109924-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS VIFOR (INTERNATIONAL) LTD. (CH) 2024-04-04 US disclosed
WO-2024023359-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS FOR USE IN THE TREATMENT, INHIBITION OF PROGRESSION, AND PREVENTION OF ECTOPIC CALCIFICATION SANIFIT THERAPEUTICS, S.A. (ES) 2024-02-01 WO disclosed
EP-4284809-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS Sanifit Therapeutics S.A. (ES) 2023-12-06 EP disclosed
WO-2022162206-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS SANIFIT THERAPEUTICS, S.A. (ES) 2022-08-04 WO disclosed
EP-4036097-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS Sanifit Therapeutics S.A. (ES) 2022-08-03 EP disclosed
EP-1626961-B1 NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME KOREA RES INST OF BIOSCIENCE (KR) 2011-11-02 EP disclosed
US-7846963-B2 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-12-07 US disclosed
US-20100286207-A1 Novel 2-Oxo-Heterocyclic Compounds And The Pharmaceutical Compositions Comprising The Same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-11-11 US disclosed
US-7723376-B2 2-oxo-heterocyclic compounds and pharmaceutical compositions KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-05-25 US disclosed
CN-1822832-A Use of novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same KOREA RES INST OF BIOSCIENCE (KR) 2006-08-23 CN disclosed
US-20060173043-A1 Use of novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2006-08-03 US disclosed
CN-1791579-A Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same KOREA RES INST OF BIOSCIENCE (KR) 2006-06-21 CN disclosed
EP-1663201-A1 A USE OF NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Korea Research Institute of Bioscience and Biotechnology (KR) 2006-06-07 EP disclosed
EP-1626961-A1 NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Korea Research Institute of Bioscience and Biotechnology (KR) 2006-02-22 EP disclosed
WO-2005004861-A1 A USE OF NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2005-01-20 WO disclosed
WO-2004101523-A1 NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2004-11-25 WO disclosed
EP-0051917-B1 BENZOFURAN ETHANOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE IN MEDICINE BEECHAM GROUP PLC (GB) 1986-02-19 EP disclosed
US-4432993-A 2-(2-BENZOFURANYL)ETHANOLAMINE BEECHAM GROUP LIMITED (GB) 1984-02-21 US disclosed
EP-0051917-A1 Benzofuran ethanolamine derivatives, processes for their preparation, and their use in medicine BEECHAM GROUP PLC (GB) 1982-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286207-A1 Novel 2-Oxo-Heterocyclic Compounds And The Pharmaceutical Compositions Comprising The Same NOD2, BMP2, NOD1 ALDH1A1 1362/4885KMT2A 4570/4885MEN1 3246/4885
US-20240109924-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS IPO4, TPX2, IPO9 ALDH1A1 4700/4885KMT2A 4555/4885MEN1 2984/4885
US-20060173043-A1 Use of novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same MALT1, BRCA1, MCL1 ALDH1A1 519/4885KMT2A 1854/4885MEN1 1200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.