SCHEMBL10561964

SCHEMBL10561964

CCSc1ncc(C(=O)O)c(=O)[nH]1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 12/20 0.74
KDM4A O75164 12/20 0.74
HIF1AN Q9NWT6 12/20 0.74
KDM2A Q9Y2K7 12/20 0.74
KDM4D Q6B0I6 11/20 0.74
KDM5B Q9UGL1 10/20 0.74
KDM3B Q7LBC6 10/20 0.74
MAPK1 P28482 1/20 0.55
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
DAO P14920 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
KDM4C Q9H3R0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4766387 0.81 KDM6B (1.00) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL11293505 0.77 ALDH1A1 (0.53) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL20060568 0.76 MAPK1 (0.61) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL23900414 0.72 KDM6B (0.61) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL13295349 0.71 KDM6B (0.56) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL23900635 0.71 KDM6B (0.51) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL2219244 0.71 KDM6B (0.60) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL11013238 0.70 CA12 (0.57) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL6556125 0.70 KDM6B (0.49) KDM6BKDM4AHIF1ANKDM2AKDM4D
SCHEMBL22868063 0.69 KDM6B (0.61) KDM6BKDM4AHIF1ANKDM2AKDM4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE32975-E FUNGICIDES, BACTERICIDES, FEED ADDITIVES BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
US-4284629-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed