Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655527 | 0.86 | ALDH1A1 (0.47) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL4680788 | 0.84 | ALDH1A1 (0.57) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL28730377 | 0.81 | MAPT (0.63) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL29550916 | 0.81 | MAPT (0.63) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL571684 | 0.80 | MAPT (0.54) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL10562125 | 0.78 | ALOX15 (0.71) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10655498 | 0.77 | ALDH1A1 (0.65) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL32667382 | 0.77 | ACHE (0.46) | MAPTALDH1A1TP53CYP3A4MEN1 | |
| SCHEMBL1616095 | 0.77 | STIM1 (0.54) | LMNARAB9AMAPK1STIM1ORAI1 | |
| SCHEMBL10564727 | 0.76 | MAPT (0.60) | MAPTALDH1A1TP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814346-A | Benzopyrans and use thereof in treating vascular diseases | ZYMA SA (CH) | 1989-03-21 | — | — | US | disclosed |
| EP-0267155-A2 | Bicyclic compounds | Zyma SA (CH) | 1988-05-11 | — | — | EP | disclosed |