Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397602 | 0.69 | CYP3A4 (0.31) | CYP3A4ALDH1A1RAB9A | |
| SCHEMBL9300565 | 0.68 | LMNA (0.37) | MEN1KMT2ALMNAL3MBTL1CYP1A2 | |
| SCHEMBL31047667 | 0.67 | CA9 (0.54) | MEN1KMT2ANPC1NPSR1CYP1A2 | |
| SCHEMBL18485382 | 0.67 | CA9 (0.54) | MEN1KMT2ANPC1NPSR1CYP1A2 | |
| SCHEMBL27488155 | 0.65 | TDP1 (0.50) | TDP1PKMMEN1KMT2ANPC1 | |
| SCHEMBL10561127 | 0.64 | LMNA (0.48) | TDP1PKMMEN1KMT2ANPC1 | |
| SCHEMBL9123400 | 0.63 | ALDH1A1 (0.48) | MEN1KMT2ANPC1LMNAL3MBTL1 | |
| SCHEMBL9003125 | 0.63 | ACHE (0.42) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL9002978 | 0.62 | EZH2 (0.40) | MEN1KMT2ACYP3A4POLBKDM4E | |
| SCHEMBL9823273 | 0.62 | TSHR (0.38) | MEN1KMT2ALMNAL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824884-A | Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers | PENNWALT CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |