Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299461 | 0.79 | POLB (0.35) | KDM4E | |
| SCHEMBL9002978 | 0.78 | EZH2 (0.40) | KMT2ACYP3A4TSHREZH2GAA | |
| SCHEMBL8333479 | 0.76 | POLB (0.40) | LMNAKMT2AKDM4EMEN1HDAC4 | |
| SCHEMBL9003125 | 0.73 | ACHE (0.42) | KMT2ACYP3A4TSHRGAAKDM4E | |
| SCHEMBL9823273 | 0.73 | TSHR (0.38) | LMNAL3MBTL1KMT2ACYP3A4TSHR | |
| SCHEMBL8338132 | 0.69 | GAA (0.46) | LMNAL3MBTL1KMT2AEZH2GAA | |
| SCHEMBL9154857 | 0.68 | CYP2C9 (0.45) | KMT2AEZH2GAAKDM4EMEN1 | |
| SCHEMBL9307823 | 0.68 | TSHR (0.49) | LMNAL3MBTL1KMT2ACYP3A4TSHR | |
| SCHEMBL10562147 | 0.68 | TDP1 (0.41) | LMNAL3MBTL1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL27839363 | 0.68 | TSHR (0.48) | LMNAL3MBTL1KMT2ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307077-A1 | Tetrahydrocarbazoles for the improvement of cyclosporin therapy | MERCK FROSST CANADA INC. (CA) | 1989-03-15 | — | — | EP | claimed |
| US-9238609-B2 | Dicarboxylic acid monomers and methods of making and using the same | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-19 | — | — | US | disclosed |
| US-20150336869-A1 | DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-11-26 | — | — | US | disclosed |
| US-20150322200-A1 | AMORPHOUS POLYESTER COMPOSITIONS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-11-12 | — | — | US | disclosed |
| US-8633265-B2 | UV stabilization of isosorbide polycarbonates | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-01-21 | — | — | US | disclosed |
| EP-2665775-A1 | UV STABILIZATION OF ISOSORBIDE POLYCARBONATES | SABIC Innovative Plastics IP B.V. (NL) | 2013-11-27 | — | — | EP | disclosed |
| CN-103328570-A | UV stabilization of isosorbide polycarbonates | SABIC INNOVATIVE PLASTICS IP | 2013-09-25 | — | — | CN | disclosed |
| WO-2012098513-A1 | UV STABILIZATION OF ISOSORBIDE POLYCARBONATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-07-26 | — | — | WO | disclosed |
| US-20120184651-A1 | UV Stabilization of Isosorbide Polycarbonates | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2012-07-19 | — | — | US | disclosed |
| US-RE34791-E | Polymer bound hindered amine light stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0303987-B1 | POLYMER BOUND HINDERED AMINE LIGHT STABILIZERS | ATOCHEM NORTH AMERICA, INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-4975489-A | Heating an anhydride-containing polymer with a hydrazine derivative of a 2,2,6,6-tetramethyl-4-aminopiperidine in an inert solvent of by melt blending | ATOCHEM NORTH AMERICA, INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4857595-A | Polymer bound hindered amine light stabilizers | PENNWALT CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4824884-A | Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers | PENNWALT CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0303987-A2 | Polymer bound hindered amine light stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0303282-A2 | Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336869-A1 | DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME | PGD, CDA, PPIA | LMNA 1827/4885L3MBTL1 2981/4885KMT2A 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.