Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092459 | 0.83 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2CASP1ALDH1A1ALOX15 | |
| SCHEMBL1623759 | 0.83 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2CASP1ALDH1A1ALOX15 | |
| SCHEMBL31092388 | 0.81 | CASP1 (0.49) | CASP1ALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL10562444 | 0.81 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2CASP1ALDH1A1ALOX15 | |
| SCHEMBL2050026 | 0.79 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2CASP1ALDH1A1KDM5B | |
| SCHEMBL28161593 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALOX15KDM5BKDM4EHCAR2 | |
| SCHEMBL29244521 | 0.76 | KDM4E (0.46) | LMNASMN1; SMN2ALDH1A1KDM5BKDM4E | |
| SCHEMBL23458578 | 0.75 | MEN1 (0.46) | LMNASMN1; SMN2CASP1ALDH1A1KDM4E | |
| SCHEMBL1623223 | 0.72 | CASP1 (0.56) | CASP1ALDH1A1KDM4EMAPT | |
| SCHEMBL8309693 | 0.71 | CA12 (0.44) | CASP1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32975-E | FUNGICIDES, BACTERICIDES, FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| US-4284629-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |