Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347782 | 0.77 | SMN1; SMN2 (0.58) | POLBHPGDALDH1A1KMT2ATDP1 | |
| SCHEMBL1849146 | 0.75 | GPR52 (0.43) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7219067 | 0.73 | CASP1 (0.64) | POLBHPGDALDH1A1KDM4EMAPT | |
| SCHEMBL1623759 | 0.71 | SMN1; SMN2 (0.53) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL31092459 | 0.71 | SMN1; SMN2 (0.53) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL10562435 | 0.71 | LMNA (0.35) | ALDH1A1KDM4EMAPTCASP1 | |
| SCHEMBL31092388 | 0.70 | CASP1 (0.49) | ALDH1A1KDM4ECASP1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL10562444 | 0.70 | SMN1; SMN2 (0.52) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL29244521 | 0.69 | KDM4E (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27750343 | 0.69 | NPC1 (0.68) | POLBHTTHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918769-A1 | SUBSTITUTED PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTI-BACTERIAL AGENTS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998001446-A1 | SUBSTITUTED PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTI-BACTERIAL AGENTS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |