Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386355 | 0.84 | NOD1 (0.54) | SLC22A12TNFNOD2NOD1VDR | |
| SCHEMBL10517908 | 0.79 | APAF1 (0.44) | LMNAKDM4EHTTHCRTR1MAPT | |
| SCHEMBL4095150 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2TNFNOD2NOD1LMNA | |
| SCHEMBL10564313 | 0.76 | CRHBP (0.42) | SLC22A12TNFNOD2NOD1VDR | |
| SCHEMBL10559177 | 0.76 | IDO1 (0.43) | SLC22A12TNFNOD2NOD1TP53 | |
| SCHEMBL4090265 | 0.75 | FGFR1 (0.54) | SMN1; SMN2TP53LMNAKDM4EHTT | |
| SCHEMBL12730136 | 0.72 | MAPK1 (0.61) | SMN1; SMN2SLC22A12LMNAKDM4EHTT | |
| SCHEMBL17456352 | 0.71 | VDR (0.70) | SMN1; SMN2TNFNOD2NOD1VDR | |
| SCHEMBL20547167 | 0.70 | TSHR (0.44) | SMN1; SMN2TNFNOD2NOD1TP53 | |
| SCHEMBL4928572 | 0.70 | KDM4E (0.50) | SMN1; SMN2LMNAKDM4EGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853400-A | IMIDAZOLE OR TRIAZOLE SUBSTITUTED INDAZOLE; | SCHERING AGROCHEMICALS LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4772613-A | Fungicides | SCHERING AGROCHEMICALS LTD. (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0247760-A2 | Benzoheterocyclic fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1987-12-02 | — | — | EP | disclosed |