Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR1B | P28222 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829918 | 0.80 | CA2 (0.49) | HTR1DHTR1AHTR1BALDH1A1DRD2 | |
| SCHEMBL11409736 | 0.79 | PTGS2 (0.44) | HTR1DHTR1AHTR1BKDM4EDRD2 | |
| SCHEMBL27454463 | 0.78 | CA2 (0.47) | HTR1DHTR1AHTR1BALDH1A1DRD2 | |
| SCHEMBL2829914 | 0.76 | DRD2 (0.44) | HTR1DDRD2DRD3DRD1DRD4 | |
| SCHEMBL22299305 | 0.75 | HDAC3 (0.43) | TSHRTYR | |
| SCHEMBL7930478 | 0.75 | CA2 (0.50) | KDM4EALDH1A1CA1CA2 | |
| SCHEMBL20526582 | 0.75 | HTR1D (0.46) | HTR1DHTR1AHTR1BALDH1A1DRD2 | |
| Iodide SCHEMBL9652564 | 0.75 | DRD2 (0.44) | HTR1DDRD2DRD3DRD1DRD4 | |
| SCHEMBL10992985 | 0.75 | TYR (0.46) | KDM4EALDH1A1GAATSHRTYR | |
| SCHEMBL9698561 | 0.74 | FUT7 (0.45) | HTR1DHTR1AHTR1BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | US | disclosed |
| WO-2011008618-A1 | METAL-CATALYZED CARBON-FLUORINE BOND FORMATION | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | FLI1, VGF, GMFG | HTR1D 4376/4885HTR1A 4363/4885HTR1B 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.