Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672417 | 0.91 | ALDH1A1 (0.38) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL10561070 | 0.86 | PKM (0.34) | LMNAALDH1A1SMN1; SMN2AKT1HTT | |
| SCHEMBL9585992 | 0.86 | ALDH1A1 (0.36) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL10565207 | 0.84 | ALDH1A1 (0.34) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL10669661 | 0.84 | LMNA (0.40) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL10563657 | 0.84 | THRB (0.38) | ALDH1A1BRAFPKMTDP1 | |
| SCHEMBL10566340 | 0.84 | PKM (0.33) | LMNAALDH1A1SMN1; SMN2AKT1NAMPT | |
| SCHEMBL9586872 | 0.83 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL9587691 | 0.83 | ALDH1A1 (0.38) | LMNAALDH1A1SMN1; SMN2HTTPKM | |
| SCHEMBL10665048 | 0.81 | SMN1; SMN2 (0.43) | LMNAALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812165-A | HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-14 | — | — | US | claimed |