Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9582360 | 0.98 | KIF11 (0.48) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL9001666 | 0.89 | LMNA (0.53) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL9582771 | 0.87 | LMNA (0.52) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL9001665 | 0.87 | LMNA (0.52) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL9583362 | 0.85 | KIF11 (0.48) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL9583254 | 0.82 | LTA4H (0.51) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL9582712 | 0.81 | LTA4H (0.50) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL5308339 | 0.77 | SLC6A2 (0.55) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL9582846 | 0.76 | LMNA (0.47) | KIF11LMNACYP2D6SLC6A2TAAR1 | |
| SCHEMBL9583586 | 0.75 | KIF11 (0.43) | KIF11LMNACYP2D6SLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822914-A | 2-amino-N-methyl-α-phenyl-phenethylamines | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-04-18 | — | — | US | claimed |