Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.69 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.69 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565877 | 0.93 | KMT2A (0.60) | ALDH1A1L3MBTL1CACNA1BAPBA1NAPRT | |
| SCHEMBL9724004 | 0.86 | KMT2A (0.71) | ALDH1A1L3MBTL1HSD17B10RECQLRAB9A | |
| SCHEMBL11327261 | 0.83 | L3MBTL1 (0.79) | ALDH1A1L3MBTL1CACNA1BAPBA1NAPRT | |
| SCHEMBL1851249 | 0.83 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1CACNA1BAPBA1NAPRT | |
| SCHEMBL2159024 | 0.83 | KMT2A (0.72) | ALDH1A1L3MBTL1CACNA1BAPBA1NAPRT | |
| SCHEMBL11414849 | 0.81 | KMT2A (0.66) | ALDH1A1L3MBTL1HSD17B10RECQLMAPT | |
| SCHEMBL863168 | 0.81 | MEN1 (0.69) | ALDH1A1L3MBTL1HSD17B10RECQLRAB9A | |
| SCHEMBL29011329 | 0.81 | CYP2C9 (0.61) | ALDH1A1L3MBTL1CACNA1BAPBA1NAPRT | |
| Acetic Acid SCHEMBL777098 | 0.80 | TSHR (0.62) | ALDH1A1L3MBTL1NAPRTHSD17B10MAPT | |
| SCHEMBL8717537 | 0.80 | LMNA (0.67) | ALDH1A1L3MBTL1NAPRTHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804661-A | ANALGESICS | CIBA-GEIGY CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |