Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563219 | 0.94 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6323372 | 0.94 | ALDH1A1 (0.68) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6305740 | 0.91 | SMN1; SMN2 (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17477113 | 0.89 | KMT2A (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17477155 | 0.88 | ALDH1A1 (0.72) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10565877 | 0.88 | KMT2A (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19890507 | 0.84 | KMT2A (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28879915 | 0.84 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8886838 | 0.83 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9551946 | 0.83 | MAPT (0.70) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101348444-B | Preparation of 2-ethoxy-4-acetaminobenzoic acid methyl ester | ZHEJIANG ESIGMA ANIMAL HEALTH CO LTD | 2012-01-11 | — | — | CN | claimed |
| CN-101348444-A | Preparation of 2-ethoxy-4-acetaminobenzoic acid methyl ester | ZHEJIANG HUINENG ANIMALS LEECH (CN) | 2009-01-21 | — | — | CN | claimed |
| US-4397763-A | TITANIUM-BASED | PHILLIPS PETROLEUM COMPANY (US) | 1983-08-09 | — | — | US | claimed |
| US-4330648-A | MIXTURE OF TITANIUM HALIDE, MAGNESIUM OR MANGANOUS CHLORIDE DIHYDROCARBYLALUMINUM HALIDE OR HYDRIDE AND AN ETHER-ALCOHOL | PHILLIPS PETROLEUM COMPANY (US) | 1982-05-18 | — | — | US | claimed |
| US-4312784-A | TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANOUS CHLORIDE, UNSATURATED HYDROCARBON AND TRIHYDROCARBYLALUMNIUM | PHILLIPS PETROLEUM CO. (US) | 1982-01-26 | — | — | US | claimed |
| US-4242480-A | TWO OR THREE COMPONENT SYSTEM COMPRISING A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANESE CHLORIDE, UNSATURATED HYDROCARBON, ORGANOALUMINUM COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-30 | — | — | US | claimed |
| EP-0002521-A1 | Titanium-magnesium/manganese-aluminum catalyst and process for olefin polymerization | PHILLIPS PETROLEUM COMPANY (US) | 1979-06-27 | — | — | EP | claimed |
| EP-0002522-A1 | Process for polymerizing butene-1 | PHILLIPS PETROLEUM COMPANY (US) | 1979-06-27 | — | — | EP | claimed |
| US-20250154115-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-05-15 | — | — | US | disclosed |
| WO-2025098450-A1 | PRMT5 INHIBITOR AND PREPARATION METHOD THEREFOR | 北京泰德制药股份有限公司 | 2025-05-15 | — | — | WO | disclosed |
| EP-4472954-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK INHIBITORS AND METHODS OF USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-115536605-B | Preparation method and application of polysubstituted oxazole compound with participation of boron reagent | 广东工业大学 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023154466-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154466-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4397763-A | TITANIUM-BASED | PHILLIPS PETROLEUM COMPANY (US) | 1983-08-09 | — | — | US | disclosed |
| US-4330648-A | MIXTURE OF TITANIUM HALIDE, MAGNESIUM OR MANGANOUS CHLORIDE DIHYDROCARBYLALUMINUM HALIDE OR HYDRIDE AND AN ETHER-ALCOHOL | PHILLIPS PETROLEUM COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4312784-A | TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANOUS CHLORIDE, UNSATURATED HYDROCARBON AND TRIHYDROCARBYLALUMNIUM | PHILLIPS PETROLEUM CO. (US) | 1982-01-26 | — | — | US | disclosed |
| US-4242480-A | TWO OR THREE COMPONENT SYSTEM COMPRISING A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANESE CHLORIDE, UNSATURATED HYDROCARBON, ORGANOALUMINUM COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0002521-A1 | Titanium-magnesium/manganese-aluminum catalyst and process for olefin polymerization | PHILLIPS PETROLEUM COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154115-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK INHIBITORS AND METHODS OF USE THEREOF | PFKL, IP6K2, IP6K1 | MEN1 4434/4885KMT2A 1686/4885SMN1; SMN2 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.