Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | SOX18 | P35713 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | MC1R | Q01726 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564438 | 0.74 | SIGMAR1 (0.36) | SIGMAR1PDPK1SOX18CYP1A2HRH3 | |
| SCHEMBL7287110 | 0.72 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL11140137 | 0.64 | CYP1A2 (0.54) | SIGMAR1PDPK1CYP1A2MC4RMC5R | |
| SCHEMBL6240981 | 0.61 | CYP1A2 (0.65) | SIGMAR1SOX18CYP1A2MC4RMC5R | |
| SCHEMBL29560700 | 0.61 | CYP1A2 (0.65) | SIGMAR1SOX18CYP1A2MC4RMC5R | |
| SCHEMBL6246604 | 0.61 | SIGMAR1 (0.68) | SIGMAR1CYP1A2HRH3TAAR1CYP2A6 | |
| SCHEMBL13555324 | 0.61 | CYP1A2 (0.50) | SIGMAR1PDPK1CYP1A2MC4RMC5R | |
| SCHEMBL1680518 | 0.61 | CYP1A2 (0.55) | SIGMAR1CYP1A2HRH3CYP2A6 | |
| Hydrochloric Acid SCHEMBL7211179 | 0.60 | SIGMAR1 (0.66) | SIGMAR1CYP1A2HRH3TAAR1CYP2A6 | |
| SCHEMBL7287783 | 0.59 | CNR2 (0.31) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |