Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7285048 | 0.80 | TAAR1 (0.34) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7295603 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL7294284 | 0.78 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL10566993 | 0.76 | — | — | |
| SCHEMBL7287783 | 0.74 | CNR2 (0.31) | ALDH1A1 | |
| SCHEMBL10566005 | 0.72 | SIGMAR1 (0.37) | ALDH1A1 | |
| SCHEMBL7286662 | 0.72 | ALDH1A1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL7286157 | 0.71 | GRIN2D (0.32) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7286224 | 0.70 | — | — | |
| SCHEMBL7283809 | 0.70 | HTR2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | claimed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |