Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566772 | 1.00 | DRD2 (0.51) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| Oxalic Acid SCHEMBL10566726 | 0.98 | DRD2 (0.49) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| Oxalic Acid SCHEMBL10566732 | 0.98 | DRD2 (0.49) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| SCHEMBL10565925 | 0.93 | DRD2 (0.49) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| Oxalic Acid SCHEMBL10567216 | 0.91 | ALDH1A1 (0.48) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| Oxalic Acid SCHEMBL10567218 | 0.91 | ALDH1A1 (0.48) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| SCHEMBL10577903 | 0.91 | ALDH1A1 (0.43) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| Oxalic Acid SCHEMBL10577726 | 0.90 | ALDH1A1 (0.46) | DRD2DRD4DRD3CYP2D6ALDH1A1 | |
| SCHEMBL10524580 | 0.89 | ADRB2 (0.44) | DRD2DRD4DRD3CYP2D6MAPK1 | |
| SCHEMBL10524588 | 0.89 | ADRB2 (0.44) | DRD2DRD4DRD3CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843085-A | LOCAL ANESTHETICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |